Health Trials

Clinical trials

2

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Condition / disease
Location
Status: Recruiting

A Study of Invikafusp Alfa (STAR0602), a Selective T Cell Receptor (TCR)-Targeting, Bifunctional Antibody-fusion Molecule, in Combination With Sacituzumab Govitecan in Participants With Advanced Solid Tumors

This is a Phase 1b/2, Open-label Study to Investigate the Safety and Efficacy of Invikafusp alfa (STAR0602), a Selective T Cell Receptor (TCR)-targeting, Bifunctional Antibody-fusion Molecule, in Combination with Sacituzumab Govitecan in Participants with Unresectable, Locally Advanced, or Metastatic Solid Tumors.

Participants needed: 50
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Marengo Therapeutics, Inc.Updated: Sep 24, 2025Locations: 8
Eligibility criteria

Have measurable disease as per RECIST v1.1 criteria and documented by CT and/or... [+2]

Vitiligo [+16]

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Status: Recruiting

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

This is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent administered intravenously in participants with advanced solid tumors that are antigen-rich.

Participants needed: 365
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Marengo Therapeutics, Inc.Updated: Jul 9, 2025Locations: 32
Eligibility criteria

Participants must have histologically confirmed solid tumors that are unresectab... [+14]

Vitiligo; [+16]

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