Clinical trials

1

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency

In this double-blinded randomised placebo-controlled clinical trial, the aim is to determine the effect of supplemental hydrocortisone compared with placebo during mild to moderate physical or mental stress on health related quality of life in patients with polymyalgia rheumatica (PMR)/giant cell arteritis (GCA) on ongoing low-dose prednisolone diagnosed with glucocorticoid-induced adrenal insufficiency. The main emphasis is on fatigue (primary outcome) and daily variation hereof during periods of stress.

Participants needed: 250
Trial details
Phase: Phase 4Age: 50+Biological sex: AllType: InterventionalSponsor: Marianne Christina KloseUpdated: Mar 16, 2026Locations: 3
Eligibility criteria

Age ≥ 50 years [+4]

Known primary or secondary adrenal insufficiency [+7]