Status: Recruiting
Clinical Trial of Mexiletine Hydrochloride for Spinal and Bulbar Muscular Atrophy
The purpose of this clinical trial is to evaluate the efficacy and safety of mexiletine hydrochloride in patients with spinal and bulbar muscular atrophy. The main questions it aims to answer are: Does mexiletine hydrochloride improve the ALSFRS-R score in spinal and bulbar muscular atrophy patients? Participants will: Take mexiletine hydrochloride or a placebo every day for 3 months Visit the hospital once every 4 weeks for evaluations.
Participants needed: 68
Trial details
Phase: Phase 2, Phase 3Age: 18-80Biological sex: MaleType: InterventionalSponsor: Masahisa KatsunoUpdated: Apr 16, 2025Locations: 5
Eligibility criteria
Male patients with a CAG repeat count of 38 or more for the androgen receptor ge... [+4]
Patients who have participated or are participating in a clinical trial within 1... [+15]