Clinical trials

2

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Condition / disease
Location
Status: Recruiting

A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

ALLTogether collects the experience of previously successful treatment of infants, children and young adults, with ALL from a number of well-renowned study groups into a new master protocol, which is both a comprehensive system for stratification and treatment of ALL in this age-group as well as the basis for several randomised and interventional trials included in the study-design.

Participants needed: 6,430
Trial details
Phase: Phase 3Age: 0-45Biological sex: AllType: InterventionalSponsor: Mats HeymanUpdated: May 5, 2026Locations: 138
Eligibility criteria

Patients newly diagnosed with T-lymphoblastic (T-cell) or B-lymphoblastic precur... [+8]

Age < 365 days and KMT2A-rearranged (KMT2A-r) BCP-ALL (documented presence of a... [+14]

Status: Recruiting

A Treatment Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

The pilot study collects the experience of previously successful treatment of infants, children and young adults, with ALL from a number of well-renowned study groups into a new platform protocol, which is both a comprehensive system for stratification and treatment of ALL in this age-group as well as the basis for several randomised trials included in the study-design. The pilot study is implemented as a master protocol without study specific interventions, thus as an observational study. The pilot study is for countries/study-groups who intend to join ALLTogether1 (including experimental interventions). For these countries the pilot study is crucial to optimise diagnostics, registration systems, collaborations with vendors, logistics and data-checks before starting the main study. The study only includes "standard of care" treatment included in the master protocol.

Participants needed: 500
Trial details
Age: 0-45Biological sex: AllType: ObservationalSponsor: Mats HeymanUpdated: Sep 2, 2025Locations: 53
Eligibility criteria

Patients newly diagnosed with T-lymphoblastic (T-cell) or B-lymphoblastic precur... [+1]

Patients with surface immunoglobulin negative (sIG-) BCP-ALL and an IG::MYC rear... [+19]