Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS Patients

This is a phase IIa, dose-ranging, proof-of-concept study of MRG-001 in patients with ARDS. The aim is to determine the safety and preliminary efficacy of MRG-001 across two dose ranges.

Participants needed: 60
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: MedRegen LLCUpdated: Aug 23, 2024
Eligibility criteria

Chest x-ray (CXR)* revealing bilateral infiltrates involving a minimum of three... [+2]

Age less than 18 years. [+9]

Status: Not yet recruiting

MRG-001 in Patients With Amyotrophic Lateral Sclerosis

The proposed study is an Open-Label, Single-Dose Study to Assess the Safety, and Pharmacodynamics (PD) signals of MRG-001 in Patients with Amyotrophic Lateral Sclerosis (ALS). MRG-001 will be administered subcutaneously 3 times per week for 2 weeks. This cycle will be repeated for 3 months. In total, patients are expected to receive 18 injections over the span of 3 months.

Participants needed: 10
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: MedRegen LLCUpdated: Aug 23, 2024
Eligibility criteria

Able to provide written informed consent (either from patient or patient's legal... [+9]

Participation in another interventional clinical trial (drug or device) within 3... [+15]

Status: Not yet recruiting

MRG-001 in Patients With Alcoholic Hepatitis

The goal of this study is to test MRG-001 (an experimental medication). The purpose of this trial is to assess the dose related safety, Pharmacokinetics, and Pharmacodynamics of MRG-001 in patients with severe alcoholic hepatitis (AH).

Participants needed: 32
Trial details
Phase: Phase 2Age: 21+Biological sex: AllType: InterventionalSponsor: MedRegen LLCUpdated: Mar 13, 2024
Eligibility criteria

Informed Consent: Able to provide written informed consent, either personally or... [+11]

Informed Consent: Inability to provide written informed consent, either personal... [+21]