Clinical trials

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Condition / disease
Location
Status: Recruiting

Intestinal Microbiota Transplantation in Patients With Chronic Heart Failure

The purpose of this study is to determine whether people with CHF, who often have different gut bacteria from healthy, would benefit from replacing their gut bacteria with healthy donor bacteria (also known as Intestinal Microbiota Transplantation - IMT). IMT aims to restore healthy gut bacteria in patients with CHF, with previous studies showing its effectiveness, but further research is needed. IMT is an approved treatment for patients with infectious diarrhea. More than 10,000 IMTs are performed every year in the US. However IMT is not approved for patients with CHF, and thus considered investigational.

Participants needed: 40
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Melana Yuzefpolskaya, MDUpdated: May 5, 2026Locations: 1
Eligibility criteria

Diagnosis of Heart Failure with Reduced Ejection Fraction (HFrEF) or Heart Failu... [+4]

Dysphagia to pills [+15]