Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

In this clinical trial, participants with chronic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine days with Xeomin injections compared to Placebo injections. Trial details include: * Trial duration: 52 to 55 weeks; * Screening period: 4 to 5 weeks; * Treatment duration: 4 treatments, each about 12 weeks apart; and * Visit frequency: about every 4 weeks, 14 visits in total. The first and last visit and the 4 treatment visits are on-site, the other 8 visits are remote by phone / video call.

Participants needed: 780
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Merz Therapeutics GmbHUpdated: Jun 25, 2026Locations: 109
Eligibility criteria

Participant has a diagnosis of CM with or without aura according to the Internat... [+3]

Diagnosis of other primary headache types, except tension-type headache, which i... [+4]

Status: Recruiting

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine

In this clinical trial, participants with episodic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine days with Xeomin injections compared to Placebo injections. Trial details include: * Trial duration: 52 to 55 weeks; * Screening period: 4 to 5 weeks; * Treatment duration: 4 treatments, each about 12 weeks apart; and * Visit frequency: about every 4 weeks, 14 visits in total. The first and last visit and the 4 treatment visits are on-site, the other 8 visits are remote by phone / video call.

Participants needed: 990
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Merz Therapeutics GmbHUpdated: Jun 25, 2026Locations: 108
Eligibility criteria

Participant has a diagnosis of EM with or without aura according to current Inte... [+3]

Diagnosis of chronic migraine; [+5]