Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Can PLIA Reduce Early Post-operative Pain After PAO Surgery?

The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main questions to answer here are: 1. Does PLIA impact post-operative pain after PAO? 2. Does PLIA impact pain medication usage as measured by morphine equivalent dosing (MED) after PAO? 3. Does the timing of PLIA administration impact post-operative pain and MED after PAO? Participants will be asked to complete some surveys; demographics survey, General Self-Efficacy Scale (GSE) and the Pain Resilience Scale. All other information will be gathered from the patients medical chart. Researchers will compare three groups. 1.) Patients who do not receive PLIA. 2.) Patients who receive PLIA after their incision is closed. 3.) Patients who receive PLIA throughout PAO.

Participants needed: 120
Trial details
Phase: Phase 2, Phase 3Age: 13-50Biological sex: AllType: InterventionalSponsor: Michael C WilleyUpdated: Apr 17, 2026Locations: 1
Eligibility criteria

Adolescent or young adult diagnosed with hip dysplasia indicated for PAO at Univ...

Unable to provide informed consent. [+4]

Status: Recruiting

Essential Amino Acid Supplementation for Femoral Fragility Fractures

This trial will evaluate the impact of 4 weeks of postoperative essential amino acid (EAA)-based supplementation on muscle morphology after femoral fragility fracture. This trial will assess the ability of EAA-based to increase skeletal muscle metabolic activity, reduce inflammation, and induce muscle fiber hypertrophy, as well as preserve skeletal muscle mass and physical performance up to 6 months after injury. Participants will be randomized in a 1:1 ratio to 1) standard of care (no dietary intervention) or 2) EAA-based supplementation.

Participants needed: 60
Trial details
Phase: Phase 2Age: 65+Biological sex: AllType: InterventionalSponsor: Michael C WilleyUpdated: Apr 15, 2026Locations: 2
Eligibility criteria

Hospital inpatient [+5]

Part of a vulnerable population (ex: Incarcerated, Non-English speaking) [+7]

Status: Not yet recruiting

Psychosocial Interventions for Young Adults With Hip Pain

Psychosocial conditions are common in young adults with hip pain including depression, anxiety, pain catastrophizing, and narcotic use. The incidence of these conditions is not well defined. Interventions to optimize psychosocial conditions with non-surgical or surgical treatments has not been investigated. The goal of this project is to determine the incidence of psychosocial conditions in the young adult population with hip pain and determine if cognitive based therapy can improve clinical outcomes in these individuals.

Participants needed: 150
Trial details
Age: 15-39Biological sex: AllType: InterventionalSponsor: Michael C WilleyUpdated: Apr 15, 2026Locations: 1
Eligibility criteria

We will enroll young adults (15-39) presenting to one of several physical therap... [+1]

Exclusion criteria will include age <15 or >40 years [+2]