Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis

This is a Phase 2, randomized, double-blind, placebo-controlled, adaptive, multicenter study to evaluate the efficacy, safety, tolerability, Pharmacodynamics (PD), and Pharmacokinetics (PK) of OATD-01 in the treatment of subjects with active pulmonary sarcoidosis.

Participants needed: 96
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Molecure S.A.Updated: Dec 12, 2025Locations: 28
Eligibility criteria

Male and female subjects with active symptomatic pulmonary sarcoidosis, (definit... [+2]

Requirement for immediate start of standard of care therapy for pulmonary sarcoi... [+14]

Status: Recruiting

First-in-human Phase I Study to Evaluate Safety, Tolerability and Antineoplastic Activity of OATD-02 in Patients with Selected Advanced And/or Metastatic Solid Tumours

The goal of this clinical trial is to learn if the OATD-02 administration (orally) in monotherapy is safe and has the pharmacodynamic potential to restore and enhance tumour responses to immunotherapy through increased arginine levels or intrinsic anti-tumour activity in participants with advanced metastatic colorectal cancer, ovarian cancer, renal cancer or pancreatic cancer.

Participants needed: 40
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Molecure S.A.Updated: Feb 24, 2025Locations: 3
Eligibility criteria

Capable of understanding and complying with protocol requirements. [+4]

Unable to take oral medications. [+6]