Clinical trials

11

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Phase I/II Clinical Study of LBL-024 in Patients With Advanced Malignant Tumors

To evaluate the phase I/II clinical study of LBL-024 in the treatment of patients with advanced malignant tumors

Participants needed: 396
Trial details
Phase: Phase 1, Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: Nanjing Leads Biolabs Co.,LtdUpdated: Jun 30, 2026Locations: 49
Eligibility criteria

Agree to comply with the trial treatment plan and visit plan, voluntarily agree... [+4]

Receiving other unmarketed clinical research drugs or treatments within 4 weeks... [+4]

Status: Recruiting

A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 02(BTC&HCC)]

An open-label, multicenter, phase II clinical study to evaluate the efficacy and safety of LBL-024 in combination with other drugs for the treatment of patients with advanced solid tumour.

Participants needed: 140
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Nanjing Leads Biolabs Co.,LtdUpdated: May 26, 2026Locations: 8
Eligibility criteria

Agree to follow the trial treatment regimen, visit schedule, laboratory test, an... [+6]

Participation in clinical studies of antineoplastic agents within 4 weeks before... [+7]

Status: Recruiting

A Phase II Clinical Study of LBL-024 Combination Therapy in Patients With Advanced Solid Tumour[Substudy 03(ESCC)]

An Open-label, Multicenter, Phase II Clinical Study to Evaluate the Efficacy and Safety of LBL-024 in Combination With Other Drugs for the Treatment of Patients With Advanced Solid Tumour.

Participants needed: 110
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Nanjing Leads Biolabs Co.,LtdUpdated: May 18, 2026Locations: 7
Eligibility criteria

Agree to follow the trial treatment regimen, visit schedule, laboratory test, an... [+6]

Participation in clinical studies of antineoplastic agents within 4 weeks before... [+7]

Status: Recruiting

A Trial of LBL-024 Monotherapy, LBL-024 Combined With LBL-007 or Toripalimab in Patients With Advanced Melanoma

This study is an open-label, multicenter phase Ib/II study to evaluate the efficacy and safety of LBL-024 monotherapy, LBL-024 in combination with LBL-007 or toripalimab in patients with advanced melanoma,To evaluate the preliminary efficacy and safety of LBL-024 monotherapy and combination therapy in patients with advanced melanoma.

Participants needed: 200
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Nanjing Leads Biolabs Co.,LtdUpdated: May 18, 2026Locations: 15
Eligibility criteria

Agree to follow the trial treatment regimen, visit schedule,laboratory test, and... [+5]

Subjects who received live vaccination within 4 weeks before the first dose or w... [+7]

Status: Recruiting

A Phase Ib/Ⅱ Clinical Trial of LBL-024 Combined With Paclitaxel in Patients With Platinum-resistant Ovarian Cancer

This trial is an open-label, multicenter phase Ib/II clinical study of LBL-024 combination therapy in patients with platinum-resistant ovarian cancer (OC),To evaluate the efficacy and safety of LBL-024 combination therapy in the treatment of advanced recurrent platinum-resistant ovarian cancer (OC) patients.

Participants needed: 110
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Nanjing Leads Biolabs Co.,LtdUpdated: May 18, 2026Locations: 13
Eligibility criteria

Agree to follow the trial treatment regimen, visit schedule, laboratory test, an... [+5]

The subject is currently participating in any other clinical trial,Or has receiv... [+8]

Status: Recruiting

A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 01(NSCLC)]

An open-label, multicenter, phase II clinical study to evaluate the efficacy and safety of LBL-024 in combination with other drugs for the treatment of patients with advanced solid tumour.

Participants needed: 230
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Nanjing Leads Biolabs Co.,LtdUpdated: May 18, 2026Locations: 24
Eligibility criteria

Agree to follow the trial treatment regimen, visit schedule, laboratory test, an... [+6]

Participation in clinical studies of antineoplastic agents within 4 weeks before... [+8]

Status: Recruiting

A Phase II Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumour[Substudy 04]

An Open-label, Multicenter, Phase II Clinical Study to Evaluate the Efficacy and Safety of LBL-024 in Combination With Other Drugs for the Treatment of Patients With Advanced Solid Tumour.

Participants needed: 110
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Nanjing Leads Biolabs Co.,LtdUpdated: May 13, 2026Locations: 7
Eligibility criteria

Agree to follow the trial treatment regimen, visit schedule, laboratory test, an... [+7]

Participation in clinical studies of antineoplastic agents within 4 weeks before... [+7]

Status: Recruiting

A Phase I Study to Assess LBL-047 in Healthy Adults and Patients With Systemic Lupus Erythematosus

A Phase I, Double-Blind, Randomized, Placebo-Controlled, Dose-Escalation Study of Single Subcutaneous Injections of LBL-047 in Healthy Adults and Patients with systemic lupus erythematosus.

Participants needed: 112
Trial details
Phase: Phase 1Age: 18-60Biological sex: AllType: InterventionalSponsor: Nanjing Leads Biolabs Co.,LtdUpdated: Apr 14, 2026Locations: 11
Eligibility criteria

Voluntarily sign and date the informed consent form (ICF) and be willing and abl... [+5]

Part A:Symptoms or history of any significant disease, including but not limited... [+8]

Status: Recruiting

A Clinical Trial of LBL-024 Combined With Etoposide and Platinum in Patients With Advanced Neuroendocrine Carcinoma

An open-label, multicenter phase Ib/II clinical study to evaluate the safety and efficacy of LBL-024 combined with etoposide and platinum in the first-line treatment of patients with advanced neuroendocrine carcinoma (NEC)

Participants needed: 178
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Nanjing Leads Biolabs Co.,LtdUpdated: Mar 12, 2026Locations: 25
Eligibility criteria

Agree to follow the trial treatment regimen and visit schedule, voluntarily enro... [+5]

Subjects who underwent major organ surgery (excluding needle biopsy) or signific... [+6]

Status: Recruiting

A Trial of LBL-024 Monotherapy or Combination Drug in Patients With Triple Negative Breast Cancer

This trial is an open-label, multicenter phase Ib/II clinical study to evaluate the efficacy and safety of LBL-024 monotherapy or in combination with albumin-bound paclitaxel in patients with recurrent or metastatic triple negative breast cancer(TNBC).

Participants needed: 220
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Nanjing Leads Biolabs Co.,LtdUpdated: Feb 12, 2026Locations: 7
Eligibility criteria

Agree to follow the trial treatment regimen, visit schedule, laboratory test, an... [+5]

Use of immunomodulatory drugs within 2 weeks prior to first dose of study drug. [+8]

Status: Recruiting

A Phase I/II Clinical Trial of LBL-034 in Patients With Relapsed Refractory Multiple Myeloma

This is a single-arm, open-label, multicenter, dose-escalation, and dose-expansion phase I/II clinical study to evaluate the safety, tolerability, pharmacokinetics, immunogenicity, and efficacy of LBL-034 in patients with Relapsed/Refractory Multiple Myeloma (R/R MM).

Participants needed: 342
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Nanjing Leads Biolabs Co.,LtdUpdated: Dec 4, 2025Locations: 26
Eligibility criteria

Agree to follow the trial treatment regimen and visit schedule, voluntarily enro... [+5]

Subjects who underwent major organ surgery (excluding needle biopsy) or signific... [+7]