Health Trials

Clinical trials

3

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of LUCAR-G79D in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE) and Idiopathic Inflammatory Myopathies (r/r IIM)

This is a prospective, single-arm, open-label and dose-escalation investigator initialed study to evaluate LUCAR-G79D in adult subjects with r/r SLE and r/r IIM.

Participants needed: 38
Trial details
Phase: Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: Nanjing Legend Biotech Co.Updated: Feb 2, 2026Locations: 5
Eligibility criteria

Subjects voluntary agreement to provide written informed consent. [+9]

Active infections such as hepatitis and tuberculosis. [+4]

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Status: Recruiting

LCAR-F33S in Treatment of Relapsed/Refractory Multiple Myeloma

A prospective, single-arm, open-label dose-exploration and expansion study to evaluate the safety, tolerability, pharmacokinetics, and antitumor efficacy characteristics of LCAR-F33S in patients with relapsed/refractory multiple myeloma(Investigator-initiated Study).

Participants needed: 35
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Nanjing Legend Biotech Co.Updated: Dec 29, 2025Locations: 4
Eligibility criteria

Subjects voluntarily participate in clinical research. [+8]

Received previous therapy targeting FcRH5 targets. [+7]

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Status: Recruiting

A Study of LUCAR-DKS1 in Subjects With Relapsed/Refractory Autoimmune Diseases

This is a prospective, single-arm, open-label and dose-escalation Investigator Initialed study to evaluate LUCAR-DKS1 in adult subjects with relapsed/refractory autoimmune diseases.

Participants needed: 36
Trial details
Phase: Early Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: Nanjing Legend Biotech Co.Updated: Dec 10, 2025Locations: 5
Eligibility criteria

Subjects voluntary agreement to provide written informed consent. [+18]

Active infections such as hepatitis and tuberculosis. [+5]

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