Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

RESTORES Trial: RESToration Of Rehabilitative Function With Epidural Spinal Stimulation

Spinal Cord Injury (SCI), being a devastating diagnosis, has little to no recovery which leads to a long-standing of debilitating impairment for affected patients. The NNI Neurosurgery team, together with our collaborators, are expanding our recruitment from our pilot trial named RESTORES: RESToration of Rehabilitative function with Epidural Spinal Stimulation. This study aims to investigate the feasibility of electrical stimulation via a spinal cord stimulator (SCS), which will be implanted into the study subjects, and advanced robotic neurorehabilitation to aid in improving neurological function in patients diagnosed with chronic SCI. An additional 15 patients on top of the 3 ongoing patients, male and female participants, above the age of 21 who have been diagnosed with the condition for more than a year will be recruited for this study over a 2-year period. Rehab sessions will take place pre and post-surgical implant, assessing subject improvements

Participants needed: 18
Trial details
Age: 21+Biological sex: AllType: InterventionalSponsor: National Neuroscience InstituteUpdated: Jan 26, 2026Locations: 1
Eligibility criteria

21 years old and older [+4]

Significant medical co-morbidities that would significantly increase the risk of... [+5]

Status: Recruiting

EGb 761 in the Syndrome of MCI With Concomitant CVD

EGb 761 has been demonstrated to be useful in improving cognitive and global clinical outcomes in patients with cognitive impairment or dementia, when administered at a daily dosage of 240mg in randomised controlled trials through several neuroprotective mechanisms of action. The study aims to determine the efficacy and safety profile of EGb 761 as a prescribed clinical drug for patients with MCI + CVD.

Participants needed: 134
Trial details
Phase: Phase 2Age: 45-85Biological sex: AllType: InterventionalSponsor: National Neuroscience InstituteUpdated: Nov 17, 2022Locations: 1
Eligibility criteria

Patients who have been diagnosed with MCI based on the Petersen criteria and Alb... [+5]

Participants should not be receiving antidepressants, antipsychotics, benzodiaze...