Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of NTX-2001 on Alcohol Consumption in Alcohol Use Disorder

The primary goal of this Phase 1b clinical trial is to evaluate the effects of a novel TAAR1 receptor partial agonist (NTX-2001) in adults with Alcohol Use Disorder (AUD). The main questions this trial aims to answer are: * Does NTX-2001 affect alcohol consumption in adults with AUD? * Is NTX-2001 safe and well tolerated in adults with AUD? Researchers will compare the effects of NTX-2001 with matching placebo (look-alike capsule that contains no drug). Participants will: * Take NTX-2001 or matching placebo every day for 2 weeks * Visit the clinic 4 times over the course of 10 weeks

Participants needed: 50
Trial details
Phase: Phase 1Age: 21-60Biological sex: AllType: InterventionalSponsor: Newleos Therapeutics, Inc.Updated: Apr 9, 2026Locations: 1
Eligibility criteria

Has provided written informed consent for the study and is willing to comply wit... [+5]

Currently seeking alcohol treatment or have been in alcohol treatment within the... [+8]

Status: Recruiting

A Study of NTX-1472 in Social Anxiety Disorder

The primary goal of this Phase 2 clinical trial is to determine the effects of a novel V1a receptor antagonist (NTX-1472) in adults with Social Anxiety Disorder (SAD). The main questions this trial aims to answer are: * Is NTX-1472 safe and well tolerated in adults with SAD? * How effectively does NTX-1472 treat adults with SAD? Researchers will compare the effects of NTX-1472 with matching placebo (a look-alike capsule that contains no drug). Participants will: * Take NTX-1472 or matching placebo every day for 8 weeks * Visit the clinic 6 times over the course of 14 weeks for checkups and tests

Participants needed: 100
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Newleos Therapeutics, Inc.Updated: Jan 21, 2026Locations: 11
Eligibility criteria

Has provided written informed consent for the study and is willing to comply wit... [+6]

Current diagnosis of performance-only SAD as defined by the DSM-5 and confirmed... [+7]