Health Trials

Clinical trials

2

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Condition / disease
Location
Status: Recruiting

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

This is a Phase 1/2, open-label, multi-center, multi-cohort, non-randomized dose escalation and dose expansion basket study to determine the safety and tolerability of NKX019 (allogeneic CAR NK cells targeting CD19) in participants with autoimmune diseases.

Participants needed: 240
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Nkarta, Inc.Updated: Jun 4, 2026Locations: 17
Eligibility criteria

Age ≥18 and ≤75 [+25]

eGFR < 45 ml/min/1.73m2 [+37]

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Status: Recruiting

A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)

This is a Phase 1/2, open-label, multi-center, multi-cohort, non-randomized dose escalation and dose expansion basket study to determine the safety and tolerability of NKX019 (allogeneic CAR NK cells targeting CD19) in participants with autoimmune diseases.

Participants needed: 120
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Nkarta, Inc.Updated: Jun 4, 2026Locations: 19
Eligibility criteria

Age ≥18 and ≤75 [+14]

eGFR < 45 ml/min/1.73 m² [+26]

Read more