Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

A prospective, multinational, randomized, double-blind, clinical trial evaluating the safety and effectiveness of a novel atrioventricular interval modulation (AVIM) algorithm downloaded into a dual-chamber Medtronic Astra/Azure pacemaker.

Participants needed: 500
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Orchestra BioMed, IncUpdated: May 27, 2026Locations: 129
Eligibility criteria

Patient has or is indicated for a dual-chamber pacemaker. Visit 1 can be perform... [+3]

LVEF <50% [+9]

Status: Recruiting

Virtue® SAB in the Treatment of Coronary ISR Trial

A prospective, multi-center, single-blind, randomized (1:1), non-inferiority study comparing clinical outcomes of the Virtue® Sirolimus AngioInfusion™ Balloon (SAB) to the AGENT™ Paclitaxel Drug-Coated Balloon (DCB) in the treatment of coronary artery in-stent restenosis (ISR).

Participants needed: 740
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Orchestra BioMed, IncUpdated: Oct 29, 2025Locations: 2
Eligibility criteria

In-stent restenosis (one or two stent layers) in a lesion previously treated wit... [+11]

Subject has a left ventricular ejection fraction < 30% within 6 months. [+10]