Clinical trials

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Condition / disease
Location
Status: Recruiting

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

The goal of this clinical trial is to determine the safety and feasibility of allogeneic transplantation with bone marrow from a deceased donor in patients with acute and chronic leukemias, myelodysplastic syndrome, and certain lymphomas. Patients will either receive myeloablative conditioning or reduced intensity conditioning regimen prior to the transplant. Patients will be followed for 56 days for safety endpoints and remain in follow-up for one year.

Participants needed: 12
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Ossium Health, Inc.Updated: Feb 24, 2026Locations: 9
Eligibility criteria

Patient has the ability to provide informed consent according to the applicable... [+12]

Availability of suitable graft from living donor (defined as 7/8 or 8/8 HLA-matc... [+5]

Status: Recruiting

HPC Offered for PRESERVE Expansion

Ossium recognizes that not all patients who could benefit from Ossium's HPC, Marrow can access the PRESERVE trial for logistical or eligibility reasons. The HOPE program is expanded access program to serve these patients by providing our bone marrow product

Participants needed: 10
Trial details
Age: 12-80Biological sex: AllType: ObservationalSponsor: Ossium Health, Inc.Updated: Aug 28, 2025Locations: 4Duration: 1 Year
Eligibility criteria

Not listed