Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Phase 2, Baseline-Controlled Study Evaluating the Safety and Efficacy of PTX-022 (Sirolimus) Topical Gel 3.9% in the Treatment of Angiokeratomas (LOTU)

The purpose of this study is to evaluate the safety and effectiveness of the experimental drug PTX-022 in the treatment of angiokeratomas

Participants needed: 15
Trial details
Phase: Phase 2Age: 6+Biological sex: AllType: InterventionalSponsor: Palvella Therapeutics, Inc.Updated: Apr 27, 2026Locations: 4
Eligibility criteria

Participants must be 6 years or older [+3]

Any significant concurrent condition that could adversely affect participation [+2]

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Status: Recruiting

A Study Evaluating the Safety and Pharmacokinetics of QTORIN Rapamycin 3.9% Anhydrous Gel in the Treatment of Adults With Pachyonychia Congenita

PALV-08 is a multicenter, open-label treatment (OLT) study enrolling adults with Pachyonychia Congenita (PC) with genotyped keratin mutations KRT6A, KRT6B, KRT6C or KRT16 who were previously enrolled in the PALV-05 (VAPAUS) trial. The purpose of this OLT study is to investigate the safety of long term exposure and pharmacokinetics (PK) of QTORIN rapamycin 3.9% anhydrous gel or "PTX-022".

Participants needed: 45
Trial details
Phase: Phase 3Age: 16+Biological sex: AllType: InterventionalSponsor: Palvella Therapeutics, Inc.Updated: Dec 9, 2022Locations: 1
Eligibility criteria

Completed the PALV-05 (VAPAUS) study [+1]

Females who are pregnant or breastfeeding [+3]

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