Clinical trials

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Condition / disease
Location
Status: Recruiting

Role of Tranexamic Acid in Reducing Hemorrhagic Events in Bariatric Surgery

The goal of this clinical trial is to learn if tranexamic acid (TXA) helps reduce bleeding during bariatric surgery, such as laparoscopic sleeve gastrectomy (LSG) and mini gastric bypass (MGB). It will also look at how safe TXA is for people undergoing these procedures. The main questions it aims to answer are: Does TXA reduce the amount of blood loss during bariatric surgery? Are there any side effects or complications in patients who receive TXA? Researchers will compare TXA to standard care (no TXA) to see if it is effective in reducing bleeding. Participants will: Receive either TXA or no TXA (placebo) before surgery Undergo standard bariatric surgery (LSG or MGB) Have their blood loss, hemoglobin levels, and any complications monitored during and after surgery

Participants needed: 140
Trial details
Phase: Phase 4Age: 18-60Biological sex: AllType: InterventionalSponsor: Patel Hospital, PakistanUpdated: Aug 1, 2025Locations: 1
Eligibility criteria

Patients above 18 years of age AND [+2]

Patients on anti-platelets/anti-coagulants [+5]

Status: Not yet recruiting

ROLE OF PROPHYLACTIC TRANEXAMIC ACID IN PREVENTION OF POST-PARTUM HEMORRHAGE IN ELLSCS

IN THIS STUDY WOMEN UNDER GOING ELLSCS WOULD BE DIVIDED INTO TWO GROUPS , ONE GROUP WOULD BE GIVEN TRANEXAMIC ACID WHILE THE OTHER WOULD BE GETTING PLACEBO PROPHYLACTICALLY TO SEE THE EFFECT OF TRANEXAMIC ACID IN PREVENTING PPH. THIS IS A RANDOMIZED CONTROLLED TRIAL. THE SAMPLING TECHNIQUE WOULD BE NON-PROBABILITY TECHNIQUE RANDOMIZATION WOULD BE DONE VIA BALLOTING METHOD.

Participants needed: 104
Trial details
Phase: Phase 1Age: 18-45Biological sex: FemaleType: InterventionalSponsor: Patel Hospital, PakistanUpdated: Jun 4, 2025Locations: 1
Eligibility criteria

Pregnant women with singleton pregnancy and low risk for PPH admitted for ELLSCS

Women with history of PPH. [+3]