Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

The primary objective of this study is to collect and evaluate clinical evidence supporting the safety and performance of the Indigo™ Aspiration System in a patient population with lower extremity acute limb ischemia (LE ALI).

Participants needed: 300
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Penumbra Inc.Updated: Jun 18, 2026Locations: 38
Eligibility criteria

Age ≥18 years [+6]

Life expectancy <1 year [+11]

Status: Recruiting

Study to Collect Real-world Performance and Safety Data on Penumbra System® in Population With Acute Ischemic Stroke (AIS).

The primary objective of this study is to collect real-world performance and safety data on the Penumbra System in a patient population with acute ischemic stroke (AIS)

Participants needed: 200
Trial details
Age: 18-75Biological sex: AllType: ObservationalSponsor: Penumbra Inc.Updated: Jun 8, 2026Locations: 10
Eligibility criteria

I.1. Patient age 18-75 years [+4]

E.1. Alberta Stroke Program Early CT Score (ASPECTS) ≤6 (for anterior circulatio... [+4]

Status: Recruiting

Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

The objective of this study is to evaluate real world long-term functional outcomes, safety and performance of the Indigo Aspiration System for the treatment of pulmonary embolism (PE).

Participants needed: 1,500
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Penumbra Inc.Updated: May 18, 2026Locations: 76
Eligibility criteria

Clinical signs and symptoms consistent with acute PE with duration of 14 days or... [+4]

Contraindication to systemic or therapeutic doses of anticoagulants (e.g. hepari... [+7]