Status: Recruiting

Advanced Imaging to Assess the Effect of Immunosuppression on Progressive Fibrosis

The purpose of this study is to investigate how immunosuppression treatment affects measurements of active collagen deposition using \[68Ga\]CBP8 positron emission tomography (PET) and tissue injury using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in individuals with non-idiopathic pulmonary fibrosis interstitial lung disease (non-IPF ILD).

Participants needed: 15

Trial details

Phase: Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: Peter CaravanUpdated: May 7, 2026Locations: 1

Eligibility criteria

Age 18-80 with a diagnosis of chronic hypersensitivity pneumonitis, connective t... [+3]

Current or prior exposure to FDA approved anti-fibrotic therapy. [+9]

Status: Recruiting

Advanced Imaging for Pulmonary Fibrosis

The purpose of this study is to determine if measurements of active collagen deposition using \[68Ga\]CBP8 positron emission tomography (PET) and tissue injury using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) can predict an individual patient's pace of disease progression in non-idiopathic pulmonary fibrosis interstitial lung disease (non-IPF ILD) and identify which individuals will develop progressive pulmonary fibrosis.

Participants needed: 60