Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of Oral Deucrictibant XR Tablet for Prophylaxis and Deucrictibant IR Capsule for On-Demand Treatment of Angioedema Attacks in Adults With Acquired Angioedema Due to C1 Inhibitor Deficiency

This is a Phase 3, multicenter, 3-part study, with 2 randomized, double-blind, placebo-controlled parts and an open-label extension part, to evaluate the efficacy and safety of orally administered deucrictibant XR tablet for prophylaxis, and deucrictibant IR capsule for on-demand treatment of angioedema attacks in adult participants aged ≥ 18 years with AAE-C1INH.

Participants needed: 32
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Pharvaris Netherlands B.V.Updated: Jun 29, 2026Locations: 32
Eligibility criteria

Provision of written informed consent [+6]

Participation in a clinical study with any other investigational drug within the... [+11]

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Status: Recruiting

Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE

This is a Phase 3, multicenter, long-term, open-label study to evaluate the safety and efficacy of once-daily orally administered deucrictibant extended-release tablet for prophylaxis to prevent angioedema attacks in participants aged ≥12 years with Hereditary Angioedema

Participants needed: 170
Trial details
Phase: Phase 3Age: 12+Biological sex: AllType: InterventionalSponsor: Pharvaris Netherlands B.V.Updated: May 7, 2026Locations: 62
Eligibility criteria

Provision of the signed ICF by the participant and/or legally designated represe... [+6]

Any diagnosis of angioedema other than HAE [+12]

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