Status: Recruiting
PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS
The purpose of this study is to test the effects of PHENOGENE-1A, which is the treatment under investigation in this study. This research will investigate if PHENOGENE-1A can help people with ALS by measuring their function using the ALS Functional Rating Scale Revised (ALSFRS-R), measuring lung function using pulmonary function tests (PFTs), such as forced vital capacity (FVC), and measuring neuro-inflammatory biomarkers in the blood.
Participants needed: 105
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: PhenoNet, Inc.Updated: Jun 9, 2026Locations: 20
Eligibility criteria
Evidence of lower motor neuron (LMN) degeneration by clinical, electrophysiologi... [+18]
ALSFRS-R score change (decrease) by 2.5 or more points between the screening vis... [+14]