Status: Recruiting
Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function
The investigators will measure blood levels of 1,5-anhydroglucitol in obese children with or without type 2 diabetes and correlate them with parameters related to functional beta-cell mass and glucose metabolism. The values will be compared to those obtained in healthy volunteers. The aim of the study is to test the validity of 1,5-anhydroglucitol as a novel biomarker of beta-cell mass and function in children with obesity with or without type 2 diabetes.
Participants needed: 50
Trial details
Age: 12-16Biological sex: AllType: ObservationalSponsor: Philippe Klee, MD-PhDUpdated: May 18, 2026Locations: 1
Eligibility criteria
Children aged 12 to 16 years [+2]
Patients with diabetes mellitus and positive autoantibodies against islets, insu... [+3]