Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of ADI-PEG 20 Versus Placebo in Subjects With High Arginine Level and Unresectable Hepatocellular Carcinoma

Evaluate efficacy and safety of ADI-PEG 20 in patients with high-argininephenotypic and HCC

Participants needed: 300
Trial details
Phase: Phase 3Age: 18-99Biological sex: AllType: InterventionalSponsor: Polaris GroupUpdated: Dec 18, 2025Locations: 11
Eligibility criteria

Prior diagnosis of HCC confirmed by radiology, histology, or cytology. [+23]

Candidate for potential curative therapies (i.e., resection or transplantation)... [+15]

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Status: Recruiting

Study of ADI-PEG 20 Versus Placebo in Subjects With NASH

Evaluate efficacy and safety of ADI-PEG 20 in patients with NASH

Participants needed: 60
Trial details
Phase: Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: Polaris GroupUpdated: Sep 23, 2025Locations: 10
Eligibility criteria

Males and non-lactating, pregnancy test negative females between 18 - 80 years o... [+22]

Weight gain or loss > 5% in the 3 months prior to randomization or > 10% in the... [+18]

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