Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases

A Phase 1 study of HBI0101 BCMA-CART in B-Cell Mediated Autoimmune Rheumatic Diseases. The goal of the study is evaluation of safety and identification of the maximum HBI0101 CART dose that may be administered safely to patients with B-cell mediated autoimmune disease.

Participants needed: 120
Trial details
Phase: Phase 1Age: 18-80Biological sex: AllType: InterventionalSponsor: Polina StepenskyUpdated: May 6, 2026Locations: 1
Eligibility criteria

Age: 18~80 years old; for patients aged ≥ 75 years, geriatric assessment and end... [+37]

CNS disease- History of CNS or spinal cord tumor, metabolic or infectious cause... [+16]

Status: Recruiting

Study of HBI0101 (NXC-201) CAR-T Therapy in Multiple Myeloma and Light-Chain Amyloidosis

A Phase II study of HBI0101 (NXC-201) BCMA-CART in Multiple Myeloma and Light-chain Amyloidosis Patients. The goal of the study is to evaluate the efficacy and safety of HBI0101 CART.

Participants needed: 180
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Polina StepenskyUpdated: May 14, 2025Locations: 1
Eligibility criteria

≥18 years of age at the time of signing informed consent. [+8]

Contraindication to a study treatment/procedure or is anticipated to receive tre... [+19]