Clinical trials

3

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis

The study objective is to establish the safety and efficacy of endovascular adjunct stenting for patients undergoing mechanical thrombectomy (MT) that are found to have residual stenosis (70-99%) following attempted clot retrieval with either aspiration catheters or stent retrievers, per device instructions for use and device labeling.

Participants needed: 342
Trial details
Phase: Phase 3Age: 18-80Biological sex: AllType: InterventionalSponsor: ProMedica Health SystemUpdated: May 22, 2026Locations: 1
Eligibility criteria

18 to 80 years of age [+10]

Females who are pregnant, or those of child-bearing potential with positive urin... [+15]

Status: Recruiting

Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy (ALLY) II Trial

The study objective is to evaluate the safety and efficacy of Intra arterial (IA) Tenecteplase (TNK) as an adjunctive therapy in acute ischemic stroke (AIS) patients with large vessel occlusions (LVO) in the anterior circulation of Internal Carotid Artery (ICA), Middle Cerebral Arteries (M1 and M2) who achieve a reperfusion grade of Modified Treatment in Cerebral Ischemia Scale (mTICI) 2b or higher post-mechanical thrombectomy using Food and Drug Administration (FDA) approved devices.

Participants needed: 132
Trial details
Phase: Phase 2, Phase 3Age: 18-85Biological sex: AllType: InterventionalSponsor: ProMedica Health SystemUpdated: Jan 21, 2026Locations: 1
Eligibility criteria

Age 18-85 [+4]

Premorbid modified Rankin scale (mRS) score >1 [+21]

Status: Not yet recruiting

Use of the PTEye Device to Reduce Inadvertent Parathyroidectomy During Thyroid Surgery

Inadvertent Parathyroidectomy (IP) during thyroid surgery may lead to transient or permanent hypoparathyroidism and hypocalcemia, which represents significant morbidity. Patients that suffer from IP and its clinical consequences often require longer duration of hospitalization and additional inpatient treatment and prescription medications. ProMedica performs a large number of endocrine procedures, so the use of novel technology to aid in the intra operative identification of parathyroid glands may ultimately offer decreased morbidity to patients. The goal of this study is to find out if using the PTEye device (a device that uses infrared light to find the Parathyroid gland) lowers the amount of times a surgeon accidentally takes out the Parathyroid gland while trying to take out the Thyroid gland in surgery.

Participants needed: 25
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: ProMedica Health SystemUpdated: Aug 11, 2025
Eligibility criteria

Patients undergoing either a total thyroidectomy or a thyroid lobectomy [+2]

Under 18 years old [+3]