Status: Not yet recruiting
Evaluation of the Efficacy and Safety of Nivolumab Neoadjuvant Treatment of Patients With Locally Advanced Oral Squamous Cell Carcinoma
This is a Phase II, single-centre, non-randomized, single-arm clinical trial to investigate the efficacy and safety of neoadjuvant nivolumab therapy in adult participants with resectable, locoregionally advanced Oral Squamous Cell Carcinoma (OSCC) tumors. Identification of predictive molecular biomarkers of tumor response to treatment will also be performed.
Participants needed: 60
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Prof. Lars Olaf CardellUpdated: Apr 7, 2026Locations: 1
Eligibility criteria
The subject is willing to participate and has given their written and dated cons... [+5]
Distant metastases (pathologically proven, radiologic or clinical evidence of di... [+28]