Status: Not yet recruiting
StAtins in Frail OldEr Patients with Ischemic Stroke or Transient Ischemic Attack - the Randomized Controlled Trial
Two Dutch guidelines (Stroke and Cardiovascular Risk Management) provide conflicting advice on optimal statin treatment in older patients. In the SAFEST - RCT, the investigators will assess the impact of starting versus not starting a statin in frail individuals aged 70 and above with a recent ischemic stroke or transient ischemic attack (TIA) on their health-related quality of life and Major Adverse Cardiovascular Events (MACE) free survival during a two-year follow-up period.
Participants needed: 612
Trial details
Phase: Phase 4Age: 70-120Biological sex: AllType: InterventionalSponsor: Prof. dr. Nathalie van der VeldeUpdated: Jan 21, 2025
Eligibility criteria
age = 70 years or older at the time of ischemic stroke or TIA; [+3]
Patients with a stroke or TIA of non-atherosclerotic etiology. [+6]