Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of PYX-201 in Advanced Solid Tumors

The primary objectives of this study are to determine the recommended dose(s) of PYX-201 for participants with recurrent/metastatic (R/M) solid tumors, and to determine the objective response rate (ORR) in participants treated with PYX-201 as a single agent.

Participants needed: 330
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Pyxis Oncology, IncUpdated: Jun 30, 2026Locations: 29
Eligibility criteria

Histologically or cytologically confirmed solid tumors including locally advance... [+27]

Status: Recruiting

Phase 1/2 Study of PYX-201 in Combination With Pembrolizumab in Advanced Solid Tumors

The primary objective of this study is to determine the recommended Phase 2 doses (RP2D(s)) and maximum tolerated dose (MTD) of PYX-201 in combination with pembrolizumab for participants with advanced solid tumors.

Participants needed: 220
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Pyxis Oncology, IncUpdated: May 4, 2026Locations: 19
Eligibility criteria

Histologically or cytologically confirmed advanced solid tumors, including first... [+9]

Known additional malignancy that is progressing or has required active treatment... [+13]