Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Evaluate Adrixetinib (Q702) in Adults With Active Chronic Graft-Versus-Host Disease

Open-label, dose escalation study to evaluate safety, tolerability pharmacokinetic and pharmacodynamic activity, and efficacy of Adrixetinib (Q702) in subjects with relapsed or refractory active chronic graft-versus-host disease (cGVHD).

Participants needed: 18
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Qurient Co., Ltd.Updated: Dec 30, 2025Locations: 8
Eligibility criteria

Subjects who are allogeneic HSCT recipients with moderate or severe active cGVHD... [+4]

Exposure to CSF1R inhibitor therapy for any indication after allogeneic transpla... [+4]

Status: Recruiting

Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors

Multicenter, open-label, dose-escalation, safety, tolerability, PK and pharmacodynamic study with a dose expansion at the RP2D to evaluate safety and potential antitumor activity of Q901 as a monotherapy and in combination with pembrolizumab

Participants needed: 130
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Qurient Co., Ltd.Updated: Aug 17, 2025Locations: 11
Eligibility criteria

Participants with histologically or cytologically confirmed advanced or metastat... [+5]

New York Heart Association Class III or IV cardiac disease, or myocardial infarc... [+3]