Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

AFFINITY BEYOND: Anti-AAV8 Antibody Assessment Study of Males With DMD

This is an observational screening study to evaluate the prevalence of anti-adeno-associated serotype 8 (AAV8) antibodies in participants with Duchenne muscular dystrophy (DMD).

Participants needed: 200
Trial details
Age: 0-25Biological sex: MaleType: ObservationalSponsor: REGENXBIO Inc.Updated: Jun 30, 2026Locations: 1
Eligibility criteria

Males at least 0 to <25 years of age [+2]

Prior participation in a gene therapy trial OR recipient of a gene therapy drug [+1]

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Status: Recruiting

AFFINITY DUCHENNE: RGX-202 Gene Therapy in Participants With Duchenne Muscular Dystrophy (DMD)

RGX-202 is a gene therapy designed to deliver a transgene for a novel microdystrophin that includes functional elements of naturally-occurring dystrophin including the C-Terminal (CT) domain. This is a multicenter, open-label dose evaluation clinical study to assess the safety, tolerability, and clinical efficacy of a one-time intravenous (IV) dose of RGX-202 in participants with Duchenne. For additional information on how to participate (or be considered for the study), please follow this link: https://mytomorro.ws/affinity-ct-gov

Participants needed: 65
Trial details
Phase: Phase 2, Phase 3Age: 1+Biological sex: MaleType: InterventionalSponsor: REGENXBIO Inc.Updated: Jun 30, 2026Locations: 17
Eligibility criteria

The participant's legal guardian(s) is (are) willing and able to provide written... [+20]

Participant has any condition that would contraindicate treatment with immunosup... [+12]

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