Clinical trials

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Condition / disease
Location
Status: Recruiting

A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy)

This is a Phase IIb randomized, clinical trial designed to assess the safety and efficacy of unilateral implantation of the CPCB-RPE1 implant in subjects with geographic atrophy involving the fovea. Up to 6 surgical implantation sites will deliver the CPCB-RPE1 in this Phase IIb clinical trial. Additional study sites may serve as referral or follow-up sites. Twenty-four (24) subjects will participate in the trial and will be randomized 3:1 to one of 2 groups: * The treatment group receiving the CPCB-RPE1 implant (up to 18 subjects). * The control group receiving a simulated "sham" implantation procedure (up to 6 subjects)

Participants needed: 24
Trial details
Phase: Phase 2Age: 55-90Biological sex: AllType: InterventionalSponsor: Regenerative Patch Technologies, LLCUpdated: Mar 25, 2026Locations: 5
Eligibility criteria

Age 55 to 90 years of age (inclusive), presenting with geographic atrophy involv... [+9]