Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Evaluate the Efficacy and Safety of RSS0343 Tablets in Patients With Chronic Obstructive Pulmonary Disease

This study is a multicenter, randomized, double-blind, placebo-controlled Phase II clinical trial designed to evaluate the efficacy and safety of RSS0343 tablets in patients with COPD. The study includes 3 study periods: a 4-week screening period, a 48-week treatment period, and a 4-week follow-up period. The primary endpoint is the annualized rate of moderate or severe exacerbations of COPD during the 48-week treatment period.

Participants needed: 300
Trial details
Phase: Phase 2Age: 40-80Biological sex: AllType: InterventionalSponsor: Reistone Biopharma Company LimitedUpdated: Jun 5, 2026Locations: 1
Eligibility criteria

Voluntarily sign a written informed consent form. [+9]

Subjects with systemic immunosuppressants, biologic agents, or Th2 cytokine inhi... [+21]

Participants needed: 600
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Reistone Biopharma Company LimitedUpdated: Apr 21, 2026Locations: 1
Eligibility criteria

Age must be ≥18 years on the day of signing the informed consent form, male or f... [+3]

Hemoglobin <100.0 g/L (for males) or <90.0 g/L (for females); [+13]

Status: Recruiting

A Clinical Study of RSS0343 in Healthy Subjects

This is a phase I study to evaluate the safety, tolerability and pharmacokinetics of RSS0343 following multiple oral doses in healthy subjects, as well as its effects on the QT/QTc interval.

Participants needed: 48
Trial details
Phase: Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: Reistone Biopharma Company LimitedUpdated: Jan 14, 2026Locations: 1
Eligibility criteria

Subjects who provided written informed consent after being fully informed of the... [+3]

Subjects who smoked more than 5 cigarettes (or equivalent nicotine products) dai... [+11]