Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of REM-422 in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma

The goal of this study is to determine the safety and antitumor effects of REM-422, a MYB mRNA degrader, in people with advanced Adenoid Cystic Carcinoma (ACC)

Participants needed: 125
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Remix TherapeuticsUpdated: Jun 24, 2026Locations: 9
Eligibility criteria

Be able to provide informed consent. [+19]

Known hypersensitivity or contraindication to any component of REM-422 or to dru... [+19]

Status: Recruiting

Study of REM-422 in Patients With AML or Higher Risk MDS

The goal of this study is to determine the safety and antitumor effects of REM-422, a MYB mRNA degrader, in people with Higher Risk MDS and relapsed/refractory AML

Participants needed: 100
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Remix TherapeuticsUpdated: Apr 23, 2025Locations: 9
Eligibility criteria

Be able to provide informed consent. [+13]

Active central nervous system (CNS) leukemia or a confirmed diagnosis of CNS leu... [+22]