Clinical trials

1

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Safety and Efficacy Study of hu14 in High-Risk Neuroblastoma Patients

Neuroblastoma is the most common type of solid cancer found outside the brain in young children. Generally, it affects children younger than 5 years old, with the average age when it is found being just 2 years. Most patients have 'high-risk' disease, with spread of the disease to different sites (metastases). This multinational study aims to find out how effective and safe the treatment of a monoclonal anti-GD2 antibody hu14.18K322A (daretabart) is when used together with chemotherapy to treat children and young people who have high-risk neuroblastoma.

Participants needed: 144
Trial details
Phase: Phase 2, Phase 3Age: 18-18Biological sex: AllType: InterventionalSponsor: Renaissance Pharma Ltd.Updated: Jun 30, 2026Locations: 5
Eligibility criteria

Are ≥18 months to <18 years of age at time of informed consent or assent. [+15]

Any active uncontrolled infection at the time of enrollment. Any known history o... [+24]