Health Trials

Clinical trials

3

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of SCG101 in the Treatment of Subjects With Hepatitis B Virus-Related Hepatocellular Carcinoma

This Phase 1/ 2a study is a multicenter study to evaluate the safety, tolerability and efficacy of SCG101 in subjects with hepatitis B virus-related hepatocellular carcinoma

Participants needed: 46
Trial details
Phase: Phase 1, Phase 2Age: 18-70Biological sex: AllType: InterventionalSponsor: SCG Cell Therapy Pte. Ltd.Updated: Feb 18, 2025Locations: 6
Eligibility criteria

Histologically or cytologically confirmed Hepatocellular carcinoma (HCC) [+9]

Subjects with history of another primary cancer [+8]

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Status: Recruiting

A Study of SCG101 TCR-T Cell Therpay in the Treatment of Subjects With Hepatitis B Virus-Related

This is a Phase I clinical study aimed to assess the safety, tolerability, and efficacy of SCG101 monotherapy for patients with HBV-HCC.

Participants needed: 38
Trial details
Phase: Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: SCG Cell Therapy Pte. Ltd.Updated: Sep 27, 2024Locations: 7
Eligibility criteria

Histologically or cytologically confirmed Hepatocellular carcinoma (HCC) [+8]

Subjects with history of another primary cancer within 5 years [+10]

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Status: Not yet recruiting

Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive Carcinoma

This is a phase 1/2, open-label, single arm, multicenter study in patients with advanced or metastatic HPV16- or HPV52-positive carcinomas who have progressed after at least one line of systemic therapy, including but not limited to combination chemotherapy and/or combination chemo-immunotherapy

Participants needed: 66
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: SCG Cell Therapy Pte. Ltd.Updated: Jul 17, 2024
Eligibility criteria

Histologically confirmed squamous cell carcinoma (SCC); may include any of the f... [+7]

Presence of clinically relevant or active seizure disorder, stroke, cerebrovascu... [+11]

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