Clinical trials

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Condition / disease
Location
Status: Recruiting

Effect of Limb Length Ratio on Roux-en-Y Gastric Bypass Outcomes (CLIMB II Study)

The investigators propose a randomized controlled trial comparing BP and roux limb lengths measuring 30 and 15% respectively of patient's total small bowel length versus current standard practice using fixed lengths. The findings would provide further insight into feasibility of standardizing RYGB limb lengths and optimizing resultant weight loss and metabolic effects. The investigators hypothesize RYGB with ratio-adjusted limb lengths (aRYGB) will result in higher total weight loss and resolution of metabolic syndrome comorbidities, including diabetes, hyperlipidemia, and hypertension compared to standard fixed-length RYGB (sRYGB). The study will also utilize the Short Form Rand 36-Item Health Survey (SF36) to determine differences in postoperative quality of life metrics.

Participants needed: 262
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Salvador NavarreteUpdated: Mar 20, 2026Locations: 1
Eligibility criteria

morbidly obese patients (defined by BMI between 40 and 60). [+2]

individuals unable to understand and sign a written consent form [+6]