Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

The RECLAIM Study.

The purpose of this study is to evaluate the safety and performance, including clinical benefit, of the PRIMUS System for the treatment of Resistant Migraine.

Participants needed: 110
Trial details
Age: 18-84Biological sex: AllType: InterventionalSponsor: Salvia BioElectronicsUpdated: Mar 27, 2026Locations: 11
Eligibility criteria

Diagnosis of migraine as defined by the ICHD-3 Classification (with or without a... [+3]

Concomitant invasive or non-invasive neuromodulation [+5]

Status: Recruiting

Response to Combined Trigeminal and Occipital Nerve Stimulation for the Preventive Treatment in Chronic Cluster Headache

This is a limited open-label study being performed at two centers in the Netherlands. All participants will receive the same treatment, and both the patients and doctors will know what that treatment is. The goal is to see how safe and effective the PRIMUS system is for preventing Chronic Cluster Headaches (CCH) in people who haven't responded well to the drug verapamil. The study will also look at the patients' experience using the system.

Participants needed: 10
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Salvia BioElectronicsUpdated: Mar 25, 2026Locations: 1
Eligibility criteria

Able and willing to provide informed consent [+2]

Any other chronic primary or secondary headache disorder, unless they can clearl... [+1]