Status: Recruiting
EXTENDed Antibiotic Durations Compared to Standard Durations for Patients With Complicated Intra-abdominal Infection.
A multicentre, open label, two-arm, parallel group, pragmatic, randomised controlled trial with internal pilot. A total of 1166 consenting adult patients with cIAI will be recruited and randomised on a 1:1 basis between 28-days antibiotics and standard care antibiotics. Patients will be followed up for 180 days to determine cost effectiveness and the rate of treatment failure in each group.
Participants needed: 1,166
Trial details
Phase: Phase 3Age: 16+Biological sex: AllType: InterventionalSponsor: Sarah CockayneUpdated: Dec 24, 2024Locations: 36
Eligibility criteria
Adults (≥ 16 years) with cIAI* (see cIAI definition) [+13]
Perforated gastric ulcer or duodenal ulcer treated within 24 hours of the onset... [+17]