Status: Recruiting
DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs
The purpose of this study is to test the safety and effectiveness of the study drug datopotamab deruxtecan in participants with metastatic breast cancer that has spread to the brain. The name of the study drug used in this research study is: Datopotamab deruxtecan (a type of antibody-drug conjugate)
Participants needed: 58
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Sarah Sammons, MDUpdated: Jul 30, 2025Locations: 3
Eligibility criteria
Metastatic breast cancer that is pathologically confirmed to be HER2-negative ac... [+20]
Visceral crisis or impending visceral crisis [+22]