Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

Ruxolitinib Cream Combined With Corticosteroids for Progressive Non-Segmental Vitiligo: A Multicenter Real-World Study

This study is a prospective, multicenter, real-world observational study to assess the clinical efficacy and safety of topical 1.5% Ruxolitinib phosphate cream used in combination with systemic corticosteroids in a real-world clinical setting. The study plans to observe patients aged 12 years and older with active, progressive non-segmental vitiligo involving the face. All treatments are prescribed based on standard routine clinical care and medical practice guidelines. Participants will apply Ruxolitinib cream twice daily to affected skin areas for up to 24 weeks alongside a standard corticosteroid regimen. The primary goal of the study is to evaluate how many patients achieve a 75% or greater improvement in their facial vitiligo patches after 12 weeks of combined treatment. Safety and side effects will also be closely monitored throughout the 24-week period.

Participants needed: 300
Trial details
Age: 12+Biological sex: AllType: ObservationalSponsor: ShanShan LiUpdated: Jul 2, 2026Locations: 12
Eligibility criteria

Age ≥ 12 years at the time of signing informed consent. [+4]

Diagnosis of other clinical forms of vitiligo (e.g., segmental vitiligo). [+8]