Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

A Phase 1b Study of ZYG24004 in Participants With Tinea Pedis Caused by Dermatophytes

This is a multicenter, randomized, double-blind, placebo-controlled Phase 1b study in adult participants with tinea pedis caused by dermatophytes. The study will evaluate the safety, local tolerability, and pharmacokinetic profile of two concentrations of ZYG24004 (1% and 3%) after topical administration once or twice (once weekly for two consecutive weeks), and will explore preliminary efficacy.

Participants needed: 64
Trial details
Phase: Phase 1Age: 18-65Biological sex: AllType: InterventionalSponsor: Sinomune Pharmaceutical Co., LtdUpdated: Jun 25, 2026Locations: 1
Eligibility criteria

Male or female participants aged 18 to 65 years; body weight >=50 kg for males a... [+6]

Hyperkeratotic tinea pedis, or tinea pedis accompanied by erosion, exudation, or... [+16]

Status: Recruiting

ZYG24002 Lotion to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy in Adult Patients With Mild to Moderate Seborrheic Dermatitis

This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group Phase Ib clinical trial conducted in adult patients with mild to moderate seborrheic dermatitis (IGA-SD score of 2-3 points). The study aims to evaluate the safety, tolerability, and steady-state pharmacokinetic (PK) profiles of three concentrations (0.5%, 0.75%, and 1.0%) of ZYG24002 Lotion following continuous topical application once daily (QD) or twice daily (BID) for 28 days, and to conduct a preliminary exploration of the drug's efficacy.

Participants needed: 48
Trial details
Phase: Phase 1Age: 18-65Biological sex: AllType: InterventionalSponsor: Sinomune Pharmaceutical Co., LtdUpdated: Jun 17, 2026Locations: 1
Eligibility criteria

Aged 18 (inclusive) to 65 (inclusive) years, of either sex. Male subjects must h... [+4]

Severe active seborrheic dermatitis: IGA-SD score of 4 points or extensive skin... [+14]