Clinical trials

4

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Study of SRSD384 in Overweight or Obese Participants

This is a two-part study, intended to investigate the safety, tolerability, characteristics of PK and PD of single SC dose of SRSD384 alone in overweight or obese participants (Part A) and in combination with tirzepatide in overweight or obese participants with T2DM (Part B).

Participants needed: 78
Trial details
Phase: Phase 1, Phase 2Age: 18-70Biological sex: AllType: InterventionalSponsor: Sirius Therapeutics Co., Ltd.Updated: Jun 5, 2026Locations: 1
Eligibility criteria

Able to comprehend and willing to sign an informed consent form (ICF) and to abi... [+3]

Obesity attributable, in the investigator's opinion, to medication use, endocrin... [+7]

Status: Recruiting

A Study of SRSD107 in Participants With Chronic Coronary and/or Peripheral Arterial Disease

The study is a Phase 2a, randomized, double-blind, placebo-controlled, sequential cohort study to evaluate the pharmacodynamics (PD), safety and pharmacokinetics (PK) of multiple doses of SRSD107 in participants with coronary arterial disease (CAD) and/or peripheral arterial disease (PAD) with aspirin as background concomitant therapy.

Participants needed: 104
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Sirius Therapeutics Co., Ltd.Updated: Apr 29, 2026Locations: 1
Eligibility criteria

Able to comprehend and willing to sign an ICF and to abide by the study restrict... [+3]

Known bleeding disorder [+5]

Status: Recruiting

A Study to Compare the Efficacy and Safety of SRSD107 and Enoxaparin in Adult Subjects Undergoing TKA

This is a Phase 2, multicenter, randomized, open-label, parallel group, blinded endpoint evaluation, active-controlled, dose-finding study.This study is designed to compare the efficacy and safety of 3 dose levels of SRSD107 and enoxaparin 40 mg daily in subjects undergoing elective primary unilateral TKA.

Participants needed: 450
Trial details
Phase: Phase 2Age: 60-80Biological sex: AllType: InterventionalSponsor: Sirius Therapeutics Co., Ltd.Updated: Jan 15, 2026Locations: 1
Eligibility criteria

Able to provide written informed consent before any study assessment is performe... [+5]

Active bleeding requiring medical or surgical intervention within 4 weeks prior... [+18]

Status: Recruiting

A Study of SRSD216 in Patients With Elevated Lipoprotein (a)

This is a two-part study, intended to investigate the safety, tolerability, characteristics of PK and PD of single SC dose of SRSD216 and to identify a dose range for further studies in subjects with elevated Lp(a) level with or without ASCVD history.

Participants needed: 84
Trial details
Phase: Phase 1, Phase 2Age: 18-70Biological sex: AllType: InterventionalSponsor: Sirius Therapeutics Co., Ltd.Updated: Jan 6, 2026Locations: 1
Eligibility criteria

Able to comprehend and willing to sign an informed consent form (ICF) and to abi... [+3]

Any history or evidence of abnormal bleeding or coagulopathy; or evidence of pro... [+7]