Clinical trials

3

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

MRI Evaluation of Graft Maturation Following ACL Reconstruction

Post-surgical ACL Graft maturation will be assessed at 4.5, 6, 7.5, 9, 10.5, and 12 months with MRI.

Participants needed: 10
Trial details
Age: 14-50Biological sex: AllType: ObservationalSponsor: Skye Biologics Holdings, LLCUpdated: Apr 24, 2026Locations: 1
Eligibility criteria

ACL tear and reconstruction; no other knee ligaments needing reconstruction [+6]

Prior surgery on the index knee within 12 months of enrollment [+14]

Status: Recruiting

Clinical Trial Evaluating an Amnion Membrane Allograft for Use in the Management of Non- Healing Diabetic Foot Ulcers Versus Standard Of Care

The main purpose of this research study is to compare the proportion of wound closure in subjects that receive E-GRAFT™ with Standard of Care (SOC) versus FIBRACOL™ with SOC. Other research purposes include the following: * Rate of wound closure * Change in ulcer size over 12 weeks * Any adverse events or reactions (side effects) * Changes in neuropathy (nerve damage) * Change in pain levels * Occurrence of infection

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Skye Biologics Holdings, LLCUpdated: Jan 10, 2025Locations: 1
Eligibility criteria

Subjects must be at least 18 years of age or older. [+11]

Target ulcers located on the plantar aspect of the foot must be offloaded for at... [+18]

Status: Recruiting

Clinical Trial Evaluating an Amnion Membrane Allograft Intended for Use in the Management of Non- Healing Venous Leg Ulcers Versus Standard Of Care Alone

The main purpose of this research study is to compare the proportion of wound closure in subjects that receive E-GRAFT™ with SOC versus FIBRACOL™ with SOC. Other research purposes include the following: * Rate of wound closure * Change in ulcer size over 12 weeks * Any adverse events or reactions (side effects) * Change in pain levels * Occurrence of infection

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Skye Biologics Holdings, LLCUpdated: Jan 9, 2025Locations: 1
Eligibility criteria

Subjects must be at least 18 years of age or older. [+3]

The subject must consent to using the prescribed off-loading method for the dura... [+24]