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Condition / disease
Location
Status: Recruiting

Topical Cryotherapy and Keloid/Hypertrophic Scars

The goal of this clinical trial is to determine whether the application of brief topical cryotherapy immediately before intralesional corticosteroid injections can reduce pain and injection resistance during routine treatment of keloid and hypertrophic scars in adult patients. The main questions it aims to answer are: Does topical cryotherapy applied before intralesional triamcinolone injection impact pain perceptions for participants with keloids or hypertrophic scars? Does topical cryotherapy affect provider-assessed injection resistance compared with standard injection alone? Researchers will split the keloid/hypertrophic scar into two halves. One half will be treated with cryotherapy followed by steroid injection, while the other half will be treated with steroid injection alone to evaluate differences in pain perception and injection resistance. Participants will rate pain after each injection using a 10-point numeric pain scale. Clinicians will rate the resistance after each injection using a 10-point numeric scale.

Participants needed: 30
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Sonal ChoudharyUpdated: Jun 12, 2026Locations: 1
Eligibility criteria

Adults (≥18 years) with keloids or hypertrophic scars already scheduled to recei... [+2]

Keloid or hypertrophic scar located on the face (except earlobes), excluded for... [+2]