Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

The Effects of 3% Trehalose Ophthalmic Solution on Corneal Epithelial Barrier Function

The purpose of this research study is to evaluate the effects of trehalose, an ingredient found in commercially available artificial tears, on the corneal barrier function. The investigators will assess corneal dryness and measure the relative corneal epithelial "barrier" function (the degree to which the cornea can prevent penetration of sodium fluorescein dye into the eye) after using eye drops that contain 3% trehalose for one month.

Participants needed: 30
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Southern California College of Optometry at Marshall B. Ketchum UniversityUpdated: May 5, 2026Locations: 1
Eligibility criteria

Adult subjects, > age 18 years, with moderate-to-severe dry eye, defined as fitt... [+2]

History or evidence of ocular or intraocular surgery in either eye within the pa... [+12]

Status: Recruiting

Trial of Vision Therapy for Intermittent Exotropia

The main objective of this randomized trial comparing vision therapy to observation is to determine the short-term effectiveness of vision therapy on distance intermittent exotropia control. The results will help determine whether to proceed to a full-scale, long-term randomized trial.

Participants needed: 58
Trial details
Age: 8-16Biological sex: AllType: InterventionalSponsor: Southern California College of Optometry at Marshall B. Ketchum UniversityUpdated: Mar 5, 2025Locations: 6
Eligibility criteria

Age 8 - 16 years [+7]

Treatment for IXT or amblyopia (other than refractive correction) within 3 month... [+3]