Health Trials

Clinical trials

2

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Condition / disease
Location
Status: Recruiting

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

CAPTAIN-T2D will take place in two parts. Part 1 (Screening) will evaluate patients with type 2 diabetes and elevated cortisol risk factors for trial eligibility and the presence of elevated cortisol. Participants deemed eligible from Part 1 will be randomized to either clofutriben or placebo in the double-blind (participant and investigator), dose-ranging, interventional Part 2 (Treatment).

Participants needed: 1,500
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Sparrow PharmaceuticalsUpdated: Jun 17, 2026Locations: 60
Eligibility criteria

From Screening 1 [+15]

New-onset diabetes (onset <1 year in the past). [+36]

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Status: Recruiting

Clofutriben Pharmacokinetics in Patients With Impaired Renal Function

This is a Phase 1, single-center, open-label, single-dose trial. Sixteen participants are planned: 8 participants with moderate renal impairment and 8 matched control participants with normal renal function.

Participants needed: 16
Trial details
Phase: Phase 1Age: 18-83Biological sex: AllType: InterventionalSponsor: Sparrow PharmaceuticalsUpdated: Dec 23, 2025Locations: 1
Eligibility criteria

Male and female participants with stable moderate renal impairment (estimated gl...

Participant whose current or recent medical conditions, medications, or procedur...

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