Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Study of STLX-2012 in Healthy Volunteers

The purpose of this research is to establish the safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of a single IV dose of STLX-2012.

Participants needed: 32
Trial details
Phase: Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: Stelexis BioSciencesUpdated: Apr 22, 2026Locations: 1
Eligibility criteria

Male or female participants aged 18-55 years old, inclusive, at Screening. [+5]

Pregnant or lactating female. [+5]

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Status: Recruiting

Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML

This is a Phase 1b open-label, multicenter, dose-escalation and dose-optimization study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and anti-tumor efficacy of eganelisib as monotherapy and in combination with cytarabine in patients with relapsed/refractory (r/r) acute myeloid leukemia (AML) or r/r higher-risk myelodysplastic syndromes (HR-MDS). The study consists of 2 parts: * Part 1: Dose Escalation (DE) in both monotherapy and in combination. * Part 2: Dose Optimization

Participants needed: 125
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Stelexis BioSciencesUpdated: Oct 22, 2025Locations: 13
Eligibility criteria

Pathological diagnosis of either: AML according to World Health Organization (WH... [+2]

Autologous or allogeneic stem cell transplant within 6 months prior to Cycle 1 D... [+4]

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