Status: Recruiting
Delayed Blood Stem Transplantation in HLA Matched Kidney Transplant Recipients to Eliminate Immunosuppressive Drugs.
The study will determine whether patients with functioning Human Leukocyte Antigen (HLA) matched kidney transplants for at least one year and who want to discontinue immunosuppressive drugs can be treated with Total Lymphoid Irradiation (TLI) and rabbit Anti-Thymocyte Globulin (rATG) and an HLA matched donor hematopoietic progenitor cell infusion such that their drugs are successfully withdrawn while maintaining normal renal function.
Participants needed: 25
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Stephan BusqueUpdated: Jul 1, 2026Locations: 1
Eligibility criteria
All consenting adults of age 18 years and older with previous HLA matched siblin... [+5]
Known allergy to ATG or a known allergy to rabbit proteins. [+6]