Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

Collagenic vs Collagen-enriched Graft in Sinus Elevation: RCT

The goal of this clinical trial is to histologically understand if collagenic or collagen enriched graft in sinus lift of healthy volunteers needing for implants in the posterior maxillae may work. The main question it aims to answer are: which material works better histologically and radiologically? Researchers will compare a collagenic graft to collagen enriched graft to see if the osteointegration of the material is the same. Participants will undergo a sinus lift with one of the two materials and after six month will undergo a bone sample collection to allow the implant insertion. twelve moths thereafter, a radiograph will be taken to measure the extension of the bone regeneration and implant behavior

Participants needed: 24
Trial details
Age: 30-80Biological sex: AllType: InterventionalSponsor: Studio Odontoiatrico Associato Dr. P. Cicchese e L. CanulloUpdated: Mar 10, 2026
Eligibility criteria

Patient requiring vertical elevation of the maxillary sinus floor. [+6]

Patients who smoke more than 5 cigarettes/day [+14]

Status: Recruiting

Prosthetic Modality and MBL

The present study will test the effect of different prosthetic modalities on conical and internal hex connection implants, assessing the radiographic MBL changes after one year. Consecutive patients fulfilling inclusion/exclusion criteria will enter the study. Once the implant is inserted, patients will be divided into three groups according to the time if their inclusion in the study. Study groups (20 patients per group): 1. Group 1: Placing Lance Conical implant with a healing abutment. Three months later, after an impression, a screw-retained restoration will be seated using a Ti-Base abutment. 2. Group 2: Placing Lance+ (Internal Hex connection) implant with a healing abutment. Three months later, after an impression, a screw-retained restoration will be seated using a Ti-Base abutment. 3. Group 3: Placing Lance Conical implant together with Connect Abutment (tightened to 30 Ncm) with a Connect healing cap ("one time one abutment"). Screw retained restoration after 3 months. Consecutive inclusion of patients - 1st- group 1, 2nd - group 2, 3rd - group 3 and vice versa. Primary outcome variable: bone level changes 12 months post-loading

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Studio Odontoiatrico Associato Dr. P. Cicchese e L. CanulloUpdated: Sep 4, 2025Locations: 1
Eligibility criteria

Male or female ≥18 years old. 2. One or more adjacent missing teeth in the poste...

Medical conditions requiring prolonged use of steroids and/or medications that c... [+13]